Can I Take Blood From a Peripheral IV Catheter?

Yes, blood can be sampled from a peripheral intravenous catheter (PIVC), but there are specific considerations and potential limitations that need to be considered for each patient.

Pros and Cons of Blood Sampling from PIVCs

ProsCons
Convenience: Avoids additional venipuncture, reducing patient discomfort and vein exhaustionContamination Risk: Higher chance of sample contamination and haemolysis
Time-Saving: Especially helpful for critically ill patientsAccuracy: May affect lab results, especially if medications were infused via PIVC
Resource-Efficient: Minimises resource use (needles, syringes)Sample Quality: Higher risk of clotted or rejected samples due to small PIVC lumen
 Device Failure: Increased risk of premature failure with excess movement and associated complications
 

Blood Cultures

Do not collect blood cultures from a PIVC on insertion or from an existing PIVC. These are associated with inaccurate results. 

Recommendations

If it is deemed clinically appropriate to sample from a PIVC, follow these recommendations to get the most accurate result:

  1. Pause any infusions for two minutes and discard 2mL of blood prior to collecting sample

  2. Use only 10mL or smaller syringes to reduce haemolysis

  3. Tourniquet time should be maximised to one minute to reduce haemoconcentration

  4. Document any samples drawn from a PIVC

  5. If assessing drug level of medication being administered, collect sample from a separate PIVC or use direct venipuncture

  6. Ensure proper flushing techniques are adhered to post collection. See our FAQ on PIVC Flushing

While blood sampling from PIVCs can be convenient and reduce patient discomfort, clinicians must weigh the risks and benefits for each patient. In cases where accurate results are crucial, direct venipuncture may be preferred due to its lower likelihood of sample alteration.

References

Australian Commission on Safety and Quality in Health Care. (2021). Management of Peripheral Intravenous Catheters Clinical Care Standard.

Cancer Nurses Society of Australia. (2024). CNSA Vascular Access Devices: Evidence-Based Clinical Practice Guidelines. https://www.cnsa.org.au/practiceresources/vascular-access-resources  

Nickel, B., Gorski, L., Kleidon, T., Kyes, A., DeVries, M., Keogh, S., Meyer, B., Sarver, M. J., Crickman, R., & Ong, J. (2024). Infusion therapy standards of practice. Journal of Infusion Nursing, 47(1S), S1-S285. 

Pittiruti, M., Van Boxtel, T., Scoppettuolo, G., Carr, P., Konstantinou, E., Ortiz Miluy, G., Lamperti, M., Goossens, G. A., Simcock, L., Dupont, C., Inwood, S., Bertoglio, S., Nicholson, J., Pinelli, F., & Pepe, G. (2023). European recommendations on the proper indication and use of peripheral venous access devices (the ERPIUP consensus): A WoCoVA project. The Journal of Vascular Access, 24(1), 165-182. https://doi.org/10.1177/11297298211023274 

Last Updated on: 08/11/2024

Got More Questions?

Meet ASK IVY, your infusion therapy companion! Powered by AI and aligned with the Infusion Therapy Standards of Practice, 9th edition, ASK IVY is your go-to resource for answers to your clinical questions.

Clinicians can streamline their workflow, save time, and enhance patient care.

  • INS members enjoy unlimited queries by logging in to the member portal below.
  • All other users are limited to 10 per month.

Address

Griffith University
Nathan
Queensland
Australia 4111